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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c267f5f6b74d886afa83e6ae90f909d6410cda76e2c9b8ac02f068ebf119a62' 
  AND token = 'Ezpu9/81VkVi90V0HEUUQV/BGkp3WzG0xTbrksUJrpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}