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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b5d801e0a816145db53cb61c1c40c7c0dbbe2c6706493c1b4256f6f7364f639' 
  AND token = 'cbBLmkOYeXnmvE0LkbgNXTcSvQ2H5ebd5jro6WHb4H4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}