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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a47e7a463837e20a819dccee8e107d5263f14070fb4dad355c29c0f163c7c225' 
  AND token = 'taY0i5xQcIUBRcEYuxBJz2xQnCi+zJVYVhNSDiP4jhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}