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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55b844d52ab6af9dcfdfcddeca724b9b6a3601250fc3705c07859d8133db28e9' 
  AND token = 'uOib6W/TODiLKWCTfUNXsi4nzjNHpFkU7SBkWvNPuIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}