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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f008f99a4e239c25e44e2a48516c531cedbcffc3a5cefe43bbb7613d05e80f74' 
  AND token = 'ywyducCJwg6Sb2pYpUUX36DTN+nC6mam7y0NhSdQaHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}