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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f3116e2aefba2355c02d246f938e6a74671df113e208be91639021e4fe75f7' 
  AND token = '1qLqSiZRTgsGil7KuNjCgraqh22TRadxApSRgTlO9fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}