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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72dd7d19e0ea938b3db78e9a1ce1831a825842b1d3887a6c44c94aa706b568bf' 
  AND token = 'xzR0h2jKjJOoeTUAG5pecg260j559kU7kKLK15YEjOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}