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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9e536cf35327678725e9d92e34be63f0153ef79266ba6c77da379afbf01524' 
  AND token = '+ItqdlI0CwDEn7dOnAqhNvyP2aeoHM/h3Y2StlbOuKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}