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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e15194e880028c880d3f11ddb93e5ffdaded811de06024820b827ba0f7b28ac9' 
  AND token = 'a5z+J/t9A/j1u+uVfUMw+Drm78+yzC6jv4xIFVX3qag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}