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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eac4dd11f421502d94d1325c9a1faba0e6b42f4e3592ca1605572c4a756590e1' 
  AND token = 'pqth1hA3WKt+u7FO4+8EX/do1MQfN+bCk2OQEz6ny1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}