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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69f80697a79aa4b8f84d93978c2a11022a9a1ebc479f246ac13b69ff24426c8b' 
  AND token = 'mQwnrMflzu7Uk6jAGp1j2gr+RSDu2xWbqOxt2m1ArPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}