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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d1da233cf1d0c0b03d692b099d54605ead396604e666abc0bd80ca5d87be13' 
  AND token = 's/7IB6nmN45g46fpQIEDFLictdJo80EBAefvVmIxS60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}