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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4821ac6ede395d3889e45259c22e0940091b4e19f5ebf9c1d1ddfa20f2712464' 
  AND token = '/vXfv/71WylhRvuqfKPT5e+9+/l1Qp2LK46/yUbXIYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}