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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d72f8fef8a529f32f1c9db8a232f08959cb60990974063cee80dd6b00ac84e7' 
  AND token = 'tk4v0c4oUuqSfg23fvwSLFGXcKrkHPihPJJNzY7CIGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}