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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ac904952d8b3afd35dd5ae4d3859c226c859aea72b72164b34a920a92af65b6' 
  AND token = 'voAYuMl4v+xS/L5WZgBeWETgEagKeuT7/MBV47eZtbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}