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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89c1d25c8c4303eb6314c2529e24012a5d486f28578f16fa3c249020cfd5c64c' 
  AND token = 'k0A5/VsYvyvs0zcE8wwlOidojyO5MYztb84nbYEKxt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}