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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d82380e88b36461b22e0b38b4039d0d30246c63324bcb67bcd79a53fd9dda0d' 
  AND token = 'QeOrL6gPCpLPkP+vNMJi7hXQQDI5Bo6mCwouGcH2YP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}