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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d12abaf86fadd1107a771d2ee2f51143a1d9eb3d5f9be2eaac4a028a66f4761' 
  AND token = 'iPWYl2fxjfe1+/VE89Lz/mDIBS7z+Zg+LH0JGl6gfyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}