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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc7540ab87fd6ac7d84185c5a81a9fe355567ef864b30391e976afa883d0935' 
  AND token = 'U3xtR4GFP6Ggei+XuYn/h9i2A5zU7SgGE8KcIFVunv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}