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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03d38eefb13e4eaa5802a1d8203c6ebf638abacc3573fc04b2df276469bb5318' 
  AND token = 'focEeMSAuS34kErfP7oC+zINHuHQkWQpt/AMm1e1dQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}