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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6677eb77e80e9c43c707689aee65e3273db0df53655cc12115611871681dffbe' 
  AND token = 'A9soK9m7oUV9StYtsvJ/tym37eAtebZI/hIgDDg7q0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}