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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4978653a1b8f6faa4ea133566ea31a7edf18f16bde956f1510ff08e10080de9f' 
  AND token = 'W2R8YrhA5rxetmcdcgxMfXFZ6SjdkykhW9u963QlidY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}