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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c645a108de9842f1aa831448ba00cfa63070ca7fc9b3c27ac5cdf91ec07904a' 
  AND token = 'WHjITnVSOnPiSVm1eosWxZE1tuogEd17IkLJUMlNjeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}