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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721e6d3440da79b4caf770c4bc0eee89f044f1e7530a38a6dfdbb86c3eb289c6' 
  AND token = 'jBpINZ61jBGij6w8TCX/En843SIqZvmCgx9yo7GA9R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}