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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b5418257f6de1bd4852475300f07fe30820fda8d9e5e5ca5d73ce4828b7ea2' 
  AND token = 'Om7gE0vKiPgXRAGKaJGOx6qg9qh+Xrhmuzky8fx9NZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}