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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce6a35d9805d676877b57d47063c7e3c04a915d0b812eb9f7d060256d6fdae50' 
  AND token = 'clzIuf90B7OySl17eGKVR7dWYWMZ9d+BRWR8F1Zn23w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}