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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51dec5247d90af2a62eefb916b76cb36f07adad6edc077c91fde92fa6f65fd7f' 
  AND token = '/DN+LCRYdhoSqaLmn3tgZ5R2cwvNhdam4i4iSF5s+sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}