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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6172334e8ea70092c2d10cd0c990d729e102b0efbf56bd9e499e567f3c7e7d4a' 
  AND token = 'NiU1Ldl8DWx6EZAAwhyTdh3L8Ia6ZG3qBUCBfCM0/LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}