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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e48bfdf344cb7e78fbfc926ec5de4c26a8004846f933e1bcaa05ec453105876' 
  AND token = 'D3bVol4Ax6MBESFvD+4TAtjc/9Qh77A30jnHHVJa5ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}