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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b1a0effc4e6576a701e9d1102524ec698e1f2550ac39432d0c19b37c021429' 
  AND token = 'kqMQQ3J4ZwbikWQF6oGD1vjg1CaNpqtHy1mWf3nSV1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}