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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4450adff3ba75a6de21fd3f739969d467460c570f83f4cbed07e35218a3d752d' 
  AND token = 'SE3ktRnBBiTOH10e3s/fckaa7+NMEhpeUcMRESOfpmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}