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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb8f96a965e9ed0c9367e9581c83b19a27f9aa37abbf2f1837f34745a61ac323' 
  AND token = 'Rxsit8rlHD3Bmel7H1jMr//h9p5JrZaLey0F1YgYm10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}