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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60b4fe65cad18b15a0e16f0e7431665d64a1ed009eb6a66981275d414c9b9904' 
  AND token = 'sC3IJtjUI2apgCKL+VobMqnMZ9hjsirKO0Rt4ko5aV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}