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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2198e55b45f77c804f99dc8fe5c1e8445aa15a85311e98c17008f70474f846d' 
  AND token = 'iYEjtatvPSMxj4eepWOT3n2fdv2vQu7HgtDjPsbF+38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}