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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd8ca2806388ecd004e698be91df17cd14af6f5d6df7fca60a512fb1c46d901' 
  AND token = 'gc+atzU/yYlkRVocPOkvvTJOcWv7UpMHwxb5+k7j/eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}