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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e52da20f9ff216a82d124677c82ce06fc2874bf7e942b36abf668496a6135028' 
  AND token = 'MV/jSIKi8YUKSgcFJYX60GCB3qjQt2H0vLkDiE2y3n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}