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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e38e8a405493bd0a7c0022f3cc73304e22ae2336948ff0af46c3b20a9332df' 
  AND token = 'o6Lt8caiGN5AfBfRkDiuBwphy71rW2MRgtorEwsWEEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}