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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165c14b1fbea4067b2c1f2f22958d4891b07572638c8e879239f4588a8bf21bb' 
  AND token = 'gqLtWqgvgmOmK0Cc682Lg/T59y1dgAMPmx0wvIO6630=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}