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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05996211e524fb4c211c6af0777de9b19763fc91905edaa6d6bed00d8d1074a4' 
  AND token = 'UEe5wa0GUoB1e5TLTK3JlHDgW4DDlaQpDiQYM9z3ID4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}