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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1972ef8380930bc7962fa0092c2b8b1d5f27aa37ba8f993c70e90b6a2034a809' 
  AND token = 'Fd3E0y/NQnm9EJViBaJJo3hnt8nt2lP8ef3SZxeAkxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}