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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b2a8819d28ca6c59a52a88f6681ccf7ca2604c6911f402c575a62c29a267c55' 
  AND token = 'kCfHYUs/OIATXQxVK5vP8cXrJ244HYRsbmioW+mPjTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}