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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e3ebd22591a7d3961fcb3d90bf60d7dee95846eace5adaaf9337540389dea8' 
  AND token = 'nlimqjYlnMaeu/3+DvALOkaIpEZ4LQ3c6IWw4vLcgVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}