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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7f2d7180d30a365792c4cd574febf091d841a16d5a3ffabeaa5b4f78a20bb24' 
  AND token = 'yZyh2vLjoWMIGMNe3oVJp13CIV9yZYNKII03Ck6bcQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}