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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bb0aebb38d7effb3528d7bfd7f96837e082c511de25637622c43334986b7143' 
  AND token = 'xOMb1Vtu3SdBhzgyGs9p0iOd533jdNi6Ot9Lzc5oXls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}