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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88c7ac70a795e50bdeceff8e8b86c44770bfc9f9b1103df7b7db68caeaa7498c' 
  AND token = 'mis2C7kJ30l0nmBDKmMxOTRcTUTbs3Kt6MS6+M9Anjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}