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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d1e2ace9106d8886ff59cfb11a2e2d49ec2f3c889f27bdf0f10bf379e80439' 
  AND token = 'EXQ16KYEtq/zjEBqNng0QAGld+916q0jwM3XH+de7XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}