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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd229f16d9912f2a7247172c8c16c4f9c9d13689aaa9aa1229a46eed49ea40f90' 
  AND token = 'URbX+XoYITOzQz1COVqsqUMRIh0+P40Bnc0jAAMnFe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}