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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '375bcc47cea1c244f9d8ee76ef6ebb5fd74a5d0b49fc9f8bffdb5d16a3b0e410' 
  AND token = '5kcYcDy1p6mB0x8w/RdmbkSW2oNgqKz6YpmiawSOmNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}