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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d0b78ce448ff04f14daf71ac0b08be9d248a6e2aa0b53f07c7f48fcb10b7c8' 
  AND token = 'wkEUYpoyk4q6318SQZ9b8hFYEhyyEgaF+zOMGR3q9xU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}