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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cf7007c458b48bcfde43bc009d7c1f8ef80fc3a1288e8228cc2553de85a0822' 
  AND token = '3pclWWE/UvwHVDtw4tzGROqFxgjZkHKCqRVMgazgNoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}